Tapentadol Prolonged Release: A Review in Pain Management
نویسندگان
چکیده
منابع مشابه
Practical considerations for the use of tapentadol prolonged release for the management of severe chronic pain.
PURPOSE Chronic pain is often challenging to address appropriately. Although patients with severe chronic pain may respond to treatment with an opioid analgesic, opioids are often associated with adverse effects that may lead patients to disrupt or discontinue therapy. In addition, opioid analgesics alone may not be effective for all types of chronic pain, including neuropathic pain. Tapentadol...
متن کاملTapentadol extended-release for treatment of chronic pain: a review
Tapentadol is a centrally acting analgesic with a dual mechanism of action of mu receptor agonism and norepinephrine reuptake inhibition. Tapentadol immediate-release is approved by the US Food and Drug Administration for the management of moderate-to-severe acute pain. It was developed to decrease the intolerability issue associated with opioids. Tapentadol extended-release has a 12-hour durat...
متن کاملTapentadol extended release for the management of chronic neck pain
BACKGROUND The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER). In this article, we present 54 patients with moderate-to-severe chronic neck pain treated with tapentadol ER. PATIENTS AND METHODS Patients received tapentadol ER 100 mg/day; dosage was then adjusted according to clinical needs. The fol...
متن کاملMethodological Issues on a Clinical Trial to Test Tapentadol Prolonged release vs. Oxycodone/Naloxone Prolonged release
To the Editor: A recent article by Baron et al. reports the results of a clinical trial (CT) to compare the effectiveness of tapentadol with oxycodone/ naloxone (Ox/Nal) for the treatment of chronic low back pain of neuropathic origin. This study is a remarkable attempt to progress in this area. We argue, however, that it contains several drawbacks that leave open ground for further trials with...
متن کاملTapentadol Prolonged Release as Used in Clinical Practice in Patients with Severe Chronic Tumor Pain
Objective: This subgroup analysis of a non-interventional study that included general practitioners and internists, assessed efficacy and safety of tapentadol prolonged release (Palexia® retard) as used in routine clinical practice in Germany for the treatment of severe chronic tumor pain. Study design: Data of all patients in the study cohort who were exclusively diagnosed with ‘tumor pain’ (n...
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ژورنال
عنوان ژورنال: Drugs
سال: 2018
ISSN: 0012-6667,1179-1950
DOI: 10.1007/s40265-018-1007-2